Some say the music industry is sinking, but those determined to salvage it will gather in Boston this weekend for the Rethink Music Conference. The Beacon will be on their tails, following the event with persistent online coverage.

The Berklee College of Music teamed up with the annual French music trade exhibition Midem to craft the conference. The event, which will be held at Hynes Convention Center April 22 to 24, aims to bring together artists, heads of labels, and the people leading the music world’s forays into new media. The three-day affair will be filled with panels, talks, and performances.

To kickstart this sonic smorgasbord, Rethink Music is holding an opening concert April 22 with Junior Boys, Yoga Girls, and Karmin. The next night, Biz Markie, the famed rapper behind “Just a Friend,” will perform at the official launch party at the Villa Victoria Center for the Arts.

The event itself features a medley of musical minds, including Boston homegirl Amanda Palmer, a solo performer and one half of the Dresden Dolls, and executives from companies like Spotify, turntable.fm, Billboard, and Pitchfork.

Aspiring musicians will have the chance to refine their artistry in sessions with Berklee professors and musicians like Portugal. The Man.

Evening showcases at the Convention Center and venues across the city will feature performances from international touring artists like Washed Out and Mayer Hawthorne.

Most importantly: The GZA will be there, likely bringing the ruckus.

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For more information on Re-Think Music, visit Rethink-music.com.